How to Take HRT

Table of Contents

Choosing the right HRT for you

There is no single ‘best’ HRT. The right choice depends on where you are in the menopause transition, whether you have a womb, your symptoms, and your preference for tablets, patches, gels or a coil.

Main types of oestrogen

  • Transdermal (patch, gel or spray): absorbed through the skin, keeps levels steady, and has the lowest clot risk.
  • Oral tablets: convenient for some women, but slightly higher clot risk than transdermal options.

If you have a womb (uterus)

You need oestrogen plus a progestogen to protect the womb lining. This can be given as combined tablets/patches, separate tablets, or via a Mirena® coil.

If you do not have a womb

You can use oestrogen-only HRT because there is no womb lining to protect.

HRT regimens

  • Sequential (cyclical) HRT: oestrogen every day plus progestogen for part of the month. Usually gives a monthly bleed. Often used in perimenopause.
  • Continuous combined HRT: oestrogen and progestogen every day. Designed to stop bleeding after the first few months. Usually used after menopause.

Starting and taking HRT safely

  • Take or apply HRT at the same time each day.
  • Do not stop suddenly without advice — talk to us if you are struggling with side effects.
  • If you miss a dose, follow the product leaflet; a single missed dose is not harmful.
  • Let us know about any new health problems or medicines.